Your thyroid gland controls the metabolism of your body. To stimulate your thyroid, your pituitary gland releases a hormone known as thyroid-stimulating hormone (TSH). Your thyroid then releases two hormones, T3 and T4. These hormones control your metabolism. Show In hypothyroidism, your thyroid doesn’t produce enough of these hormones. This is also known as an underactive thyroid. There are three types of hypothyroidism: primary, secondary, and tertiary. In primary hypothyroidism, your thyroid is being stimulated properly. However, it isn’t able to produce enough thyroid hormones for your body to function properly. This means that your thyroid itself is the source of the problem. In secondary hypothyroidism, your pituitary gland isn’t stimulating your thyroid to produce enough hormones. In other words, the problem isn’t with your thyroid. The same is true with tertiary hypothyroidism. The most common cause of primary hypothyroidism is Hashimoto’s thyroiditis. This is an autoimmune disease that causes your immune system to mistakenly attack your thyroid. You might also develop primary hypothyroidism for a number of other reasons. If you had hyperthyroidism (or overactive thyroid), your treatment may have left you with hypothyroidism. A common treatment for hyperthyroidism is radioactive iodine. This treatment destroys the thyroid. A less common treatment for hyperthyroidism involves the surgical removal of part or all of the thyroid. Both can result in hypothyroidism. If you had thyroid cancer, your doctor would have surgically removed your thyroid, or part of it, to treat the cancer. Other possible causes of hypothyroidism include:
In some cases, a woman might develop hypothyroidism after giving birth. According to the National Institutes of Health, the disease is most common in women and people over 60 years old. The symptoms of hypothyroidism vary widely from person to person. Symptoms typically develop slowly, and depend on the severity of the disease. At first, you may notice general symptoms including:
Because the thyroid hormones control the metabolism of all your cells, you might also gain weight. Other possible symptoms include:
As the disease progresses, these symptoms gradually become more severe. If your hypothyroidism is extremely severe, you might fall into a coma, known as a myxedema coma. This is a life-threatening condition. If you show physical symptoms of hypothyroidism, your doctor might decide to do tests to check whether you have this condition. Your doctor will generally use a blood test to check your T4 and TSH levels. If your thyroid is malfunctioning, your pituitary gland will produce more TSH in an attempt to get your thyroid to produce more T3 and T4. An elevated TSH level can indicate to your doctor that you have a thyroid problem. Treatment for hypothyroidism involves taking medication to replace the missing thyroid hormones. Your doctor will typically start you on a low dose and increase it gradually. The goal is for your levels of thyroid hormones to return to within the normal range. You’ll continue to take your thyroid medication throughout your life. Your medication replaces the thyroid hormones that your thyroid is unable to produce. It does not correct your thyroid disease. This means that if you stop taking it, your symptoms will return. Some medications and foods can interfere with your medications. Make sure to tell your doctor about all medications that you take, including over-the-counter drugs. Some vitamins and supplements, especially those for iron and calcium, can also interfere with your treatment. You should talk with your doctor about any supplements you’re taking. You may also need to cut back on eating anything made from soy and some high-fiber foods. The causes of hypothyroidism are broadly classified as primary and secondary. Primary hypothyroidism relates to defects/disease of the thyroid itself and are further delineated below. The most common cause is an autoimmune mechanism, where the body perceives healthy and normally functioning thyroidal tissue or products as foreign and attacks them.
Secondary hypothyroidism is attributed to an insufficient stimulation of the thyroid, most commonly due to lack of thyroid-stimulating hormone (TSH) production from the pituitary gland.
What are the symptoms of secondary hypothyroidism?Symptoms:. Weakness.. Fatigue.. Cold intolerance.. Constipation.. Weight gain.. Depression.. Joint or muscle pain.. Brittle fingernails.. How do you know if thyroid is primary or secondary?Diagnosis of Hypothyroidism
In primary hypothyroidism, there is decreased feedback inhibition of the intact pituitary, and serum TSH is always elevated, whereas serum free T4 is low. In secondary hypothyroidism, free T4 and serum TSH are low (sometimes TSH is normal but with decreased bioactivity).
Whats the difference between primary and secondary hyperthyroidism?Primary hyperthyroidism is the term used when the pathology is within the thyroid gland. Secondary hyperthyroidism is the term used when the thyroid gland is stimulated by excessive thyroid-stimulating hormone (TSH) in the circulation.
What does secondary hypothyroidism mean?Secondary hypothyroidism is a rare disorder that describes an underactive pituitary gland causing an underactive thyroid. The pituitary gland produces thyroid-stimulating hormone, also called thyrotropin. As you can tell from the name, this pituitary hormone is needed for normal thyroid function.
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What is the difference between primary and secondary hypothyroidism
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