Can high prolactin levels cause a false positive pregnancy test

Learn the reasons for a false-positive test result

Is the stick always right? Usually yes, but sometimes no. Learn about the rare reasons for a false-positive pregnancy test.

A home pregnancy test has confirmed what you suspected — you’re pregnant. Home pregnancy tests work by detecting the presence of the pregnancy hormone hCG in your urine. Their results are considered reliable, especially when you wait for at least a week after you miss your period to use one.

They’re not foolproof, however. It is possible to get a positive result when you’re not actually pregnant, which is called a false-positive. If you’ve been looking forward to a positive pregnancy test result, a false-positive is disappointing. The good news is they’re rare. The best thing to do when you’ve gotten a positive result is to contact your doctor. A blood test will confirm that you’re pregnant.

4 Causes of a False Positive Pregnancy Test

The four main causes that may lead to a false positive pregnancy test include a chemical pregnancy, a recent miscarriage, medication or a defective test. Read below to learn more about each of these scenarios.

Chemical pregnancy

A chemical pregnancy is a pregnancy, but an unhealthy one that results in an early miscarriage. A chemical pregnancy occurs when an egg has fertilized but doesn’t attach to the uterus. Usually, you will have a heavy period soon after your period is normally due. It’s estimated that 25-40 percent of pregnancies end as undetected miscarriages.

Recent miscarriage or birth

If you’ve had a baby recently or a miscarriage, you may test positive for pregnancy. When you’re pregnant, hCG levels rise quickly and peak at about 10 weeks. When a pregnancy ends, the levels go down, but slowly. The hormone can remain in your blood and urine for up to six weeks after a pregnancy ends.

Medications

If you’re undergoing fertility treatments to become pregnant, you may be getting hCG injections to stimulate ovulation. The medication can cause a false-positive result if you take the test too soon after a missed period.

Medications that may cause a false positive pregnancy:

  • Antihistamines
  • Antianxiety medications
  • Antipsychotics
  • Diuretics
  • Parkinson’s disease medications
  • Methadone

Defective pregnancy test or user error

Before buying a home pregnancy test, check to make sure it hasn’t expired. If it has, the chemical used to detect hCG may not work. It’s important to read and follow the test instructions carefully. For instance, some tests require leaving the dipstick in the urine stream for a specific amount of time. Taking the test too early can also result in a false-positive.

How to Avoid a False-Positive Pregnancy Test

The best way to avoid a false-positive pregnancy test is to wait at least a week after you’ve missed your period to take the test. The level of hCG hormone will be higher and easier to detect. Detecting a chemical pregnancy before it miscarries can be emotionally hard.

Many home pregnancy test kits include two tests. If you get a positive result, you can wait a couple of days and use the second test. Then contact your doctor for a blood test to confirm the good news!

Looking for an OB/GYN? We can help!

Home pregnancy tests are a common tool used to find out if you’re expecting. Most at-home pregnancy tests are dipsticks that are placed in a urine stream. The stick is then able to detect human chorionic gonadotropin (hCG), which is a hormone produced during early pregnancy.

Some pregnancy tests detect hCG very early in pregnancy. Reputable home pregnancy tests can be highly accurate, but they are not foolproof.

False-positive and false-negative tests can occur for a variety of reasons. It’s also important to remember that once you have a positive pregnancy test, it’s important to talk with your doctor about beginning early prenatal care.

Read on to learn more about false positives on home pregnancy tests.

It’s possible to have a positive pregnancy test even if you aren’t technically pregnant. This is called a false positive.

It’s sometimes caused by a chemical pregnancy. A chemical pregnancy occurs if a fertilized egg, known as the embryo, is unable to implant, or grow, very early on. This can happen for many reasons.

Some causes of chemical pregnancies are unknown.

They are thought to be very common, but they typically go undetected if a pregnancy test isn’t taken. These early test results, when wrong, can be emotionally draining.

For that reason, it’s recommended you wait until 1 week after you expected your period to start to use an at-home pregnancy test.

Sometimes a fertilized egg can implant itself outside of the main cavity of the uterus, which causes an ectopic pregnancy. An ectopic pregnancy is a serious medical emergency and must be addressed immediately.

Ectopic pregnancies usually happen if a fertilized egg gets stuck in a fallopian tube during its journey to the uterus. This type of ectopic pregnancy is also known as a tubal pregnancy.

An ectopic pregnancy can just happen, but risk factors include:

  • scar tissue or inflammation in the fallopian tube
  • misshapen fallopian tube or other congenital anomalies
  • a history of infertility treatments such as in vitro fertilization (IVF)
  • a history of uterine or tubal surgery
  • a history of past uterine infections
  • a history of a prior ectopic pregnancy

Ectopic pregnancies can also occur in the cervix, ovary, or abdominal cavity.

An ectopic pregnancy is a medical emergency. It can’t continue to become a normal pregnancy and it can be damaging to the woman if left untreated.. The embryo isn’t viable because there’s no place for it to grow or thrive outside of the uterus.

Extreme blood loss or loss of the reproductive organs can occur. Bleeding and pain in early pregnancy need to be evaluated by a medical professional immediately.

The embryo will still produce hCG, even though it has implanted in the wrong place. That can cause a false-positive reading on an at-home pregnancy test.

Symptoms of ectopic pregnancy include:

  • sharp waves of pain in the abdomen, pelvis, shoulder, or neck
  • severe pain on one side of the abdomen
  • light to heavy vaginal spotting or bleeding
  • dizziness or fainting
  • pressure on your rectum

Seek immediate medical help if you suspect you have an ectopic pregnancy.

You may continue to test positive for pregnancy following the loss of a pregnancy, either through miscarriage or abortion.

During pregnancy, the hCG levels continue to rise, in general doubling every few days, and peaking at around 10 weeks. This is before the placenta is formed and functional around week 12.

The hormone can remain in your blood and urine for up to 6 weeks following the end of the pregnancy. It’s possible to have a false-positive test until your hCG levels return to their prepregnancy state.

If the miscarriage was spontaneous, it’s also possible that not all the pregnancy-related tissue was eliminated. This can cause hCG levels to remain elevated, among other more worrisome symptoms such as ongoing bleeding or fever.

An ultrasound is generally needed to determine if an intrauterine pregnancy is identified, lost, or if there is a fetus without cardiac activity.

When this occurs, sometimes a minor surgical procedure called a dilation and curettage (D and C) is often required to remove the tissue, depending upon your symptoms and how far along the pregnancy was.

At-home pregnancy tests aren’t foolproof. It’s important to follow package directions exactly. Check the expiration date before using the test.

Even with these safeguards, user error can occur. One of the most common mistakes is taking the test too early during your cycle. This can cause either a false negative or a false positive

It’s also important to use the test when your urine isn’t diluted excessively with water. Use the test when your urine is very concentrated, like when you first wake up in the morning.

Leaving the dipstick in your urine stream for the exact amount of time allotted is also important. Consider setting a timer on a stopwatch or your phone. That can help you track how long the dipstick has been in your urine stream.

You’ll want to use a timer again while you wait for your results. Checking your results during the result time frame is also important.

Sometimes an evaporation line can be mistaken for a positive pregnancy test. Some at-home tests show two lines when hCG is detected and one line when hCG isn’t detected.

The lines are usually a bright color, such as pink, red, or blue. Sometimes, a faint-colored second line will appear. This line may represent an early pregnancy, or it may be an evaporation line.

It’s probably an evaporation line if the line is completely colorless.

Evaporation lines may show up on a test you view after your urine has evaporated completely. Sometimes they’re caused by hormonal levels that don’t represent pregnancy.

The best way to try and prevent being confused by an evaporation line is to follow the test’s timing directions exactly as they’re given.

If you’re trying to become pregnant under a doctor’s care, you may be taking fertility medications.

One of these is the synthetic hCG trigger shot, sold under the following brand names:

  • Novarel
  • Pregnyl
  • Ovidrel
  • Profasi

The hCG shot helps follicles release mature eggs. It may cause a false-positive reading on an at-home pregnancy test, particularly if the test is taken too early.

Other medications can also cause false-positive pregnancy tests. They include but aren’t limited to:

  • anti-anxiety medications, like diazepam (Valium) or alprazolam (Xanax)
  • antipsychotics, such as clozapine or chlorpromazine
  • anticonvulsants, like phenobarbital or other barbiturates
  • Parkinson’s disease medications, including bromocriptine (Parlodel)
  • diuretics, like furosemide (Lasix, Diuscreen)
  • antihistamines, including promethazine
  • methadone (Dolophine)

A positive at-home pregnancy test result should always be followed up with a doctor’s appointment. Your doctor may give you a urine or blood test to confirm the results and monitor your hCG levels.

They may also order a transvaginal ultrasound to confirm that the pregnancy is proceeding normally. A follow-up ultrasound may be needed after about 1 week — if it’s early — to verify the results.

If you’ve received a false positive, your doctor’s visit will determine that. Depending on your situation, it might be a relief to find out you’re not pregnant.

But if you were excited by your early results, it can be very upsetting. Remember that false positives do happen and are not an indication that you cannot become pregnant in the future.

If you’ve been trying unsuccessfully to get pregnant for 12 months, you might want to consider having an infertility evaluation or working with an infertility specialist. Women ages 35 and older who have been trying unsuccessfully to get pregnant for 6 months are recommended to seek an infertility evaluation.

There are support groups where you can find inspiration and obtain knowledge from women who have been through the same thing.

Working one-on-one with a therapist, family member, or trusted friend can also be beneficial.

Can high prolactin cause false pregnancy?

Women on drugs which increase the prolactin levels may experience galactorrhea, which may give rise to the illusion of pregnancy.

Can prolactin interfere with hCG?

Prolactin-secreting pituitary implants alone, on the other hand, while exerting small effects on 3 beta-HSD expression and activity, led to a marked potentiation of the stimulatory effect of hCG on all parameters.

Can High hormones cause a false positive pregnancy test?

Sometimes, women who are post-menopausal or going through menopause have high levels of HCG, which could cause a pregnancy test to show as positive even though you wouldn't truly be pregnant.

What medical conditions can cause a false positive pregnancy test?

However, in rare instances, you can get a false positive from: a recent pregnancy (e.g. after miscarriage, recent birth or termination) some rare ovarian cysts. certain medications containing the hCG hormone, like some fertility treatments.

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